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Article

Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome.

Cell - 17 Feb 2012

Xie Wei, Barr Cathy L, Kim Audrey, Yue Feng, Lee Ah Young, Eubanks James, Dempster Emma L, Ren Bing

Abstract excerpt

Differential methylation of the two parental genomes in placental mammals is essential for genomic imprinting and embryogenesis. To systematically study this epigenetic process, we have generated a base-resolution, allele-specific DNA methylation (ASM) map in the mouse genome. We find parent-of-origin dependent (imprinted) ASM at 1,952 CG dinucleotides. These imprinted CGs form 55 discrete clusters including...

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Identifiers

PMID: 22341451
DOI: 10.1016/j.cell.2011.12.035
PMCID: PMC3343639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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