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Article

A Resource for the Allele-Specific Analysis of DNA Methylation at Multiple Genomically Imprinted Loci in Mice.

G3 (Bethesda, Md.) - 4 Jan 2018

Wasson Jadiel A, Birol Onur, Katz David J

Abstract excerpt

Genomically imprinted loci are expressed mono-allelically, dependent upon the parent of origin. Their regulation not only illuminates how chromatin regulates gene expression but also how chromatin can be reprogrammed every generation. Because of their distinct parent-of-origin regulation, analysis of imprinted loci can be difficult. Single nucleotide polymorphisms (SNPs) are required to accurately assess these...

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Identifiers

PMID: 29138238
DOI: 10.1534/g3.117.300417
PMCID: PMC5765370

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