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DNA Methylation Divergence and Tissue Specialization in the Developing Mouse Placenta

18 Mar 2017

Abstract excerpt

The placental epigenome plays a vital role in regulating mammalian growth and development. Aberrations in placental DNA methylation are linked to several disease states, including intrauterine growth restriction and preeclampsia. Studying the evolution and development of the placental epigenome is critical to understanding the origin and progression of such diseases. Although high-resolution studies have found...

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PMID: 28379409
DOI: 10.1093/molbev/msx112

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