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Article

Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study.

Malaria journal - 15 Feb 2012

Greene Jennifer A, Sam-Agudu Nadia, John Chandy C, Opoka Robert O, Zimmerman Peter A, Kazura James W

Abstract excerpt

BACKGROUND: In malaria endemic areas, host genetics influence whether a Plasmodium falciparum-infected child develops uncomplicated or severe malaria. TLR2 has been identified as a receptor for P. falciparum-derived glycosylphosphatidylinositol (GPI), and polymorphisms within the TLR2 gene may af...

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Source

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Identifiers

PMID: 22336003
DOI: 10.1186/1475-2875-11-47
PMCID: PMC3306729

Genes

TLR2
GPI
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22336003-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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