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Article

Toll-like receptor polymorphisms in malaria-endemic populations.

Malaria journal - 24 Mar 2009

Greene Jennifer A, Moormann Ann M, Vulule John, Bockarie Moses J, Zimmerman Peter A, Kazura James W

Abstract excerpt

BACKGROUND: Toll-like receptors (TLR) and related downstream signaling pathways of innate immunity have been implicated in the pathogenesis of Plasmodium falciparum malaria. Because of their potential role in malaria pathogenesis, polymorphisms in these genes may be under selective pressure in populations where this infectious disease is endemic. METHODS: A post-PCR Ligation Detection Reaction-Fluorescent...

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Source

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Identifiers

PMID: 19317913
DOI: 10.1186/1475-2875-8-50
PMCID: PMC2667436

Genes

TLR2
TLR9
MAL
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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