Article
Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria.
The Journal of communicable diseases - 1 Mar 2006
Mockenhaupt F P, Cramer J P, Hamann L, Stegemann M S, Eckert J, Oh Na-Ri, Otchwemah R N, Dietz E, Ehrhardt S, Schröder N W J, Bienzle U, Schumann R R
Abstract excerpt
Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year. Recently, members of the toll-like receptor (TLR) family have been shown to be involved in recognition of the etiologic organism Plasmodium fal...
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