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Article

Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, India.

Immunologic research - 1 Feb 2016

Panigrahi Subhendu, Kar Avishek, Tripathy Sagnika, Mohapatra Manoj K, Dhangadamajhi Gunanidhi

Abstract excerpt

Although the role of TLRs signalling in malaria pathogenesis is well established, contribution of individual TLR to clinical outcome of malaria still remains inconclusive. Given the importance of TLR2 and its co-receptors in recognising distinct structural forms of key malaria toxins and mediating innate immune response, it is essential to delineate their genetic contribution. Variants in TLR1 (I602S) and TLR6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26621243
DOI: 10.1007/s12026-015-8749-7

Genes

TLR2
TLR6
TLR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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