Article
[Relationship between mutations of epidermal growth factor receptor gene and clinicopathologic features of non-small cell lung cancers].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2011
Wang Fang, Fu Sha, Tang Tao, Deng Ling, Zhang Xiao, Li Yin-zhen, Shao Jian-yong
Abstract excerpt
OBJECTIVE: To explore the relationship between the mutations of epidermal growth factor receptor (EGFR) gene and clinicopathological characteristics in patients with non-small cell lung cancers (NSCLC). METHODS: Paraffin-embedded tissue specimens were obtained from 1444 patients with NSCLC. The genomic DNA was extracted. Mutations of EGFR gene (exons 19 and 21) were detected by real-time PCR. RESULTS: DNA was...
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