Article
[Detection of epidermal growth factor receptor mutations in non-small-cell lung carcinoma by direct sequencing and correlations with clinicopathological characteristics and sample types].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2011
Sun Meng-hong, Yang Fei, Shen Lei, Zhang Ling, Chen Ying, Cai Xu, Zhu Xiao-li, Zhou Xiao-yan
Abstract excerpt
OBJECTIVE: To retrospectively analyze epidermal growth factor receptor (EGFR) gene mutation frequencies and distribution characteristics in Chinese patients with non-small-cell lung carcinoma (NSCLC) by direct gene sequencing. METHODS: Clinical samples from 443 NSCLC patients were obtained for EGFR gene mutation analysis, including 299 surgical specimens, 59 core biopsies and 85 fine needle aspiration and pleural...
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