Article
[Detection of epidermal growth factor receptor gene mutations and its clinical significance in non-small cell lung cancers].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2011
Zhao Jing, Zhu Yan, Zhang Li, Yu Yong-wei, Zheng Jian-ming
Abstract excerpt
OBJECTIVE: To investigate the detection technology and its clinical significance of the EGFR gene mutation in non-small cell lung cancer. METHODS: DNA direct sequencing methods by PCR amplification were used to detect EGFR gene exons 18-21 mutation and to analyze its clinical pathological significance in 192 patients with non-small cell lung cancer. RESULTS: 64 of the 192 cases presented with EGFR gene tyrosine...
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