Article
[Status and clinicopathologic implication of epidermal growth factor receptor mutation in non-small cell carcinoma of lung].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Jul 2007
Xu Mei-lin, Liu Yan, Zhong Hao-hao, Wu Bing-quan
Abstract excerpt
OBJECTIVE: To investigate mutations of epidermal growth factor receptor (EGFR) exon 19 and 21 in non-small cell lung carcinoma and to explore their clinicopathological correlations. METHOD: DNA was extracted from the excised tumor specimens of 66 non-small cell lung carcinoma patients by traditional phenol-chloroform and ethanol precipitation. Exons 19 and 21 were amplified by polymerase chain reaction (PCR),...
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