Article
[Analysis of EGFR mutations in 176 cases of non-small cell lung cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 2006
Dong Qiang-gang, Han Bao-hui, Huang Jin-su, Yang Li-ming, Huang Jian, Zhao Chun-ying, Lu Li-qin
Abstract excerpt
OBJECTIVE: To analyze the incidence and profile of mutations in epidermal growth factor receptor (EGFR) in Chinese patients with non-small cell lung cancer (NSCLC). METHODS: A total of 176 cases of NSCLC tissue was enrolled in this study, among which 123 normal lung samples were also included. The tissue DNA was extracted and the EGFR gene in exon 19 to 21 was subjected for PCR amplification and direct...
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