Article
[EGFR gene mutation status among lung cancer patients in China].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Apr 2007
Li Qi, Zhao Ya-li, Hao Hao-jie, Li Xiang-hong
Abstract excerpt
OBJECTIVE: To investigate EGFR gene mutations in non-small cell lung cancers (NSCLCs) and their correlation with clinicopathologic features and clinical characteristics in Chinese NSCLC patients. METHODS: To analyse EGFR mutations of exons 19 and 21 in NSCLCs by PCR amplification and sequencing. RESULTS: Somatic mutations in TK domain of EGFR were found in 13 cases (17.3%), the majority of mutations were in-frame...
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