Article
Relationship between epidermal growth factor receptor gene mutations and clinicopathological features in patients with non-small cell lung cancer in western Turkey.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Unal Olcun Umit, Oztop Ilhan, Calibasi Gizem, Baskin Yasemin, Koca Dogan, Demir Necla, Akman Tulay, Ellidokuz Hulya, Yilmaz Ahmet Ugur
Abstract excerpt
BACKGROUND: To investigate epidermal growth factor receptor (EGFR) gene mutations in patients with non- small cell lung cancer (NSCLC) and to analyze any relationship with clinicopathological features and prognosis. MATERIALS AND METHODS: EGFR gene exons 18-21 in 48 specimens of paraffin-embedded tumor tissue from NSCLC patients were amplified by PCR, followed by direct sequencing and analysis of links to...
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