Article
Clinicopathologic significance of the mutations of the epidermal growth factor receptor gene in patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2005
Tomizawa Yoshio, Iijima Hironobu, Sunaga Noriaki, Sato Koji, Takise Atsushi, Otani Yoshimi, Tanaka Shigefumi, Suga Tatsuo, Saito Ryusei, Ishizuka Tamotsu, Dobashi Kunio, Minna John D, Nakajima Takashi, Mori Masatomo
Abstract excerpt
PURPOSE: It has been reported that the mutations of epidermal growth factor receptor (EGFR) are detected in lung cancers. Studies of EGFR mutations in large numbers of patients' tumors with clinical data including response to EGFR tyrosine kinase directed therapy are needed to develop a robust database for clinical use. The purpose of the present study is to gain further insights into the significance of EGFR...
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