Article
Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease.
Kidney international - 1 May 2012
Zheng Dong, Cao Qi, Lee Vincent W S, Wang Ya, Zheng Guoping, Wang YuanMin, Tan Thian Kui, Wang Changqi, Alexander Stephen I, Harris David C H, Wang Yiping
Abstract excerpt
Plasmacytoid dendritic cells play important roles in inducing immune tolerance, preventing allograft rejection, and regulating immune responses in both autoimmune disease and graft-versus-host disease. In order to evaluate a possible protective effect of plasmacytoid dendritic cells against renal inflammation and injury, we purified these cells from mouse spleens and adoptively transferred lipopolysaccharide...
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