Article
Structure and function of renal macrophages and dendritic cells from lupus-prone mice.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Jun 2014
Sahu Ranjit, Bethunaickan Ramalingam, Singh Satwinder, Davidson Anne
Abstract excerpt
OBJECTIVE: To characterize renal macrophages and dendritic cells (DCs) in 2 murine models of lupus nephritis. METHODS: We used a bead-based enrichment step followed by cell sorting to isolate populations of interest from young mice and nephritic mice. Cell morphology was examined by microscopy. Arginase and nitrite production was examined using biochemical assays. The antigen-presenting functions of the cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
