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Article

Human plasmacytoid dendritic cells acquire phagocytic capacity by TLR9 ligation in the presence of soluble factors produced by renal epithelial cells.

Kidney international - 1 Feb 2018

Ruben Jurjen M, García-Romo Gina Stella, Breman Eytan, van der Kooij Sandra, Redeker Anke, Arens Ramon, van Kooten Cees

Abstract excerpt

Plasmacytoid dendritic cells (pDCs) are antigen presenting cells specialized in viral recognition through Toll-like receptor (TLR)7 and TLR9, and produce vast amounts of interferon alpha upon ligation of these TLRs. We had previously demonstrated a strong influx of pDCs in the tubulointerstitium of renal biopsies at the time of acute rejection. However, the role of human pDCs in mediating acute or chronic...

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Source

Identifiers

PMID: 29061332
DOI: 10.1016/j.kint.2017.08.006

Genes

TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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