Dendritic cells in acute kidney injury: cues from the microenvironment.

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Article

Dendritic cells in acute kidney injury: cues from the microenvironment.

Transactions of the American Clinical and Climatological Association - 1 Jan 2012

Okusa Mark D, Li Li

Abstract excerpt

Dendritic cells (DCs) and macrophages are critical early initiators of innate immunity in the kidney; they also orchestrate inflammation subsequent to ischemia-reperfusion injury. Hence, these cells hold great promise as targets for pharmacological interventions. Macrophages and DCs are the most abundant leukocytes present in the kidney, and they represent a heterogeneous population of cells that are capable of...

Topics

Acute Kidney Injury
Animals
Cellular Microenvironment
Dendritic Cells
Disease Models, Animal
Kidney
Killer Cells, Natural
Macrophages
Mice
Phenotype
Receptors, Purinergic P1
Reperfusion Injury
T-Lymphocytes

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Identifiers

PMID: 23303968
PMCID: PMC3540592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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