Article
Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis.
Journal of the American Society of Nephrology : JASN - 1 Mar 2004
Krüger Thilo, Benke Dirk, Eitner Frank, Lang Andreas, Wirtz Monika, Hamilton-Williams Emma E, Engel Daniel, Giese Bernd, Müller-Newen Gerhard, Floege Jürgen, Kurts Christian
Abstract excerpt
The kidney tubulointerstitium contains numerous bone marrow-derived antigen-presenting cells, which are often referred to as resident tissue macrophages, although several previous studies had demonstrated characteristics of dendritic cells (DC). In this study, we describe a subset of tubulointerstitial cells expressing the DC marker CD11c. A protocol was established to isolate these cells for in vitro analysis....
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