Dendritic Cells and Macrophages: Sentinels in the Kidney.

doi:10.2215/CJN.07100714

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Article

Dendritic Cells and Macrophages: Sentinels in the Kidney.

Clinical journal of the American Society of Nephrology : CJASN - 7 Oct 2015

Weisheit Christina K, Engel Daniel R, Kurts Christian

Abstract excerpt

The mononuclear phagocytes (dendritic cells and macrophages) are closely related immune cells with central roles in anti-infectious defense and maintenance of organ integrity. The canonical function of dendritic cells is the activation of T cells, whereas macrophages remove apoptotic cells and microbes by phagocytosis. In the kidney, these cell types form an intricate system of mononuclear phagocytes that surveys...

Topics

Animals
Dendritic Cells
Humans
Immune Tolerance
Immunotherapy
Kidney
Kidney Diseases
Kidney Transplantation
Macrophages
Phenotype
Receptors, Pattern Recognition
Urinary Tract Infections

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Identifiers

PMID: 25568218
DOI: 10.2215/CJN.07100714
PMCID: PMC4594071

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