Article
Analysis of TNF-mediated recruitment and activation of glomerular dendritic cells in mouse kidneys by compartment-specific flow cytometry.
Kidney international - 1 Jul 2013
Schwarz Martin, Taubitz Anela, Eltrich Nuru, Mulay Shrikant R, Allam Ramanjaneyulu, Vielhauer Volker
Abstract excerpt
Renal dendritic cells (DCs) form an interstitial network contributing to inflammatory and adaptive immune responses in the kidney. The presence and functional role of DC-like glomerular CD11c(+) mononuclear phagocytes is a matter of debate. Using compartment-specific flow cytometry we found that healthy mouse kidneys contained 1.3 CD11c(+) cells per 100 glomeruli and these increased by 4.6-fold and 13-fold after...
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