Article
Dendritic cells and macrophages in the kidney: a spectrum of good and evil.
Nature reviews. Nephrology - 1 Nov 2014
Rogers Natasha M, Ferenbach David A, Isenberg Jeffrey S, Thomson Angus W, Hughes Jeremy
Abstract excerpt
Renal dendritic cells (DCs) and macrophages represent a constitutive, extensive and contiguous network of innate immune cells that provide sentinel and immune-intelligence activity; they induce and regulate inflammatory responses to freely filtered antigenic material and protect the kidney from infection. Tissue-resident or infiltrating DCs and macrophages are key factors in the initiation and propagation of...
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