Article
Effect on risk of anencephaly of gene-nutrient interactions between methylenetetrahydrofolate reductase C677T polymorphism and maternal folate, vitamin B12 and homocysteine profile.
Public health nutrition - 1 Aug 2012
Lacasaña Marina, Blanco-Muñoz Julia, Borja-Aburto Victor H, Aguilar-Garduño Clemente, Rodríguez-Barranco Miguel, Sierra-Ramirez José A, Galaviz-Hernandez Carlos, Gonzalez-Alzaga Beatriz, Garcia-Cavazos Ricardo
Abstract excerpt
OBJECTIVE: To evaluate the effects on anencephaly risk of the interaction between the maternal profile of folate, vitamin B12 and homocysteine and the 677C→T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR). DESIGN: Case-control study paired (1:1) on maternity clinic, date of birth and state of residence. Cases of anencephaly were identified using the Registry of the Mexican Neural...
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