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Article

Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells.

Journal of cell science - 15 Dec 2011

Popova Milena K, He Wei, Korenjak Michael, Dyson Nicholas J, Moon Nam-Sung

Abstract excerpt

Retinoblastoma tumor suppressor protein (pRb) regulates various biological processes during development and tumorigenesis. Although the molecular mechanism by which pRb controls cell cycle progression is well characterized, how pRb promotes cell-type specification and differentiation is less understood. Here, we report that Extra Macrochaetae (EMC), the Drosophila homolog of inhibitor of DNA...

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PMID: 22193959
DOI: 10.1242/jcs.088773
PMCID: PMC3258105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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