Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation.

G3 (Bethesda, Md.) - 3 Oct 2013

Collins Heather, Moon Nam-Sung

Abstract excerpt

A Polycomb group protein, Posterior sex combs (Psc), was identified in a genetic screen designed to find factors that can specifically induce morphological defects in rbf1 mutant eyes. We discovered that rbf1 mutations enhance developmental phenotypes caused by Psc overexpression such as ectopic cell death and disorganized ommatidia. Our genetic analysis revealed that Psc-induced developmental defects are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to DNA-Binding Proteins
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Phenotype

Share to Polycomb Repressive Complex 1

Share to Retinoblastoma Protein

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23893745
DOI: 10.1534/g3.113.007419
PMCID: PMC3789789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation.PMID 23893745Read ↗

The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development.Semantic proximity Read ↗

Mutating RBF can enhance its pro-apoptotic activity and uncovers a new role in tissue homeostasis.Semantic proximity Read ↗

Regulation of apoptosis of rbf mutant cells during Drosophila development.Semantic proximity Read ↗

The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis.Semantic proximity Read ↗

Mutation of zebrafish caf-1b results in S phase arrest, defective differentiation, and p53-mediated apoptosis during organogenesis.Semantic proximity Read ↗

Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain.Semantic proximity Read ↗

Rbf1 degron dysfunction enhances cellular DNA replication.Semantic proximity Read ↗

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.Semantic proximity Read ↗

Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene.Semantic proximity Read ↗

The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA.Semantic proximity Read ↗

The COP1-ADA2b module mediates light regulation of DNA double-strand break repair in Arabidopsis.Semantic proximity Read ↗

Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.