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Article

The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis.

The EMBO journal - 15 Feb 1999

Du W, Dyson N

Abstract excerpt

The first appearance of G1 during Drosophila embryogenesis, at cell cycle 17, is accompanied by the down-regulation of E2F-dependent transcription. Mutant alleles of rbf were generated and analyzed to determine the role of RBF in this process. Embryos lacking both maternal and zygotic RBF products show constitutive expression of PCNA and RNR2, two E2F-regulated genes, indicating that RBF is required for their...

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Identifiers

PMID: 10022834
DOI: 10.1093/emboj/18.4.916
PMCID: PMC1171184

Genes

PCNA

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