Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis.

The EMBO journal - 15 Feb 1999

Du W, Dyson N

Abstract excerpt

The first appearance of G1 during Drosophila embryogenesis, at cell cycle 17, is accompanied by the down-regulation of E2F-dependent transcription. Mutant alleles of rbf were generated and analyzed to determine the role of RBF in this process. Embryos lacking both maternal and zygotic RBF product...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinases
Share to Cyclin E
Share to E2F Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to G1 Phase

Share to Microscopy, Electron, Scanning

Share to Retinoblastoma-Binding Protein 1

Share to Retinoblastoma Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 10022834
DOI: 10.1093/emboj/18.4.916
PMCID: PMC1171184

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10022834-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis.PMID 10022834Read ↗

Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis.Semantic proximity Read ↗

Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain.Semantic proximity Read ↗

The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth.Semantic proximity Read ↗

RBF and Rno promote photoreceptor differentiation onset through modulating EGFR signaling in the Drosophila developing eye.Semantic proximity Read ↗

Rbf1 degron dysfunction enhances cellular DNA replication.Semantic proximity Read ↗

RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.Semantic proximity Read ↗

Rbf Regulates Drosophila Spermatogenesis via Control of Somatic Stem and Progenitor Cell Fate in the Larval Testis.Semantic proximity Read ↗

The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation.Semantic proximity Read ↗

Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development.Semantic proximity Read ↗

Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes.Semantic proximity Read ↗

Regulation of apoptosis of rbf mutant cells during Drosophila development.Semantic proximity Read ↗

S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.