Article
Regulation of apoptosis of rbf mutant cells during Drosophila development.
Developmental biology - 15 Feb 2009
Tanaka-Matakatsu Miho, Xu Jinhua, Cheng Leping, Du Wei
Abstract excerpt
Inactivation of the retinoblastoma gene Rb leads to defects in cell proliferation, differentiation, or apoptosis, depending on specific cell or tissue types. To gain insights into the genes that can modulate the consequences of Rb inactivation, we carried out a genetic screen in Drosophila to identify mutations that affected apoptosis induced by inactivation of the Retinoblastoma-family protein (rbf) and...
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