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Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in <i>Drosophila</i> prostate-like secondary cells

2021-03-27

Abstract excerpt

Dysregulation of cell cycle components results in the development and progression of several cancer types. Unusually, loss of the tumour suppressor gene, Retinoblastoma (Rb), and consequent activation of transcription factor E2F1 have been linked to late-stage tumour progression in prostate cancer, rather than early-stage events. This change is associated with an androgen-independent form of cancer, castration-re...

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Literature Corpus work
5f65ebff-d398-568c-97ee-ddb227cbf862
DOI
10.1101/2021.03.27.437310
Open publication

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Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in <i>Drosophila</i> prostate-like secondary cellsDOI 10.1101/2021.03.27.437310
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