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Article

ERp44 C160S/C212S mutants regulate IP3R1 channel activity.

Protein & cell - 1 Dec 2011

Pan Congyan, Zheng Ji, Wu Yanyun, Chen Yingxiao, Wang Likun, Zhou Zhansong, Yin Wenxuan, Ji Guangju

Abstract excerpt

Previous studies have indicated that ERp44 inhibits inositol 1,4,5-trisphosphate (IP(3))-induced Ca(2+) release (IICR) via IP(3)R(1), but the mechanism remains largely unexplored. Using extracellular ATP to induce intracellular calcium transient as an IICR model, Ca(2+) image, pull down assay, and Western blotting experiments were carried out in the present study. We found that extracellular ATP induced calcium...

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Identifiers

PMID: 22183808
DOI: 10.1007/s13238-011-1116-0
PMCID: PMC4875245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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