Article
Store-operated channels: diversity and activation mechanisms.
Science's STKE : signal transduction knowledge environment - 20 Jul 2004
Bolotina Victoria M
Abstract excerpt
This perspective addresses two questions: How many store-operated channels (SOCs) are there, and how many mechanisms can account for SOC activation by depleted stores? Accumulating evidence suggests that the SOC family is not limited to the calcium-selective SOC that is responsible for ICRAC (Ca2+-SOC), but includes poorly selective cation SOCs (cat-SOCs) that may satisfy physiological needs in diverse excitable...
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