A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32.

doi:10.1182/blood-2011-03-343921

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Article

A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32.

Blood - 12 Jan 2012

Cozen Wendy, Li Dalin, Best Timothy, Van Den Berg David J, Gourraud Pierre-Antoine, Cortessis Victoria K, Skol Andrew D, Mack Thomas M, Glaser Sally L, Weiss Lawrence M, Nathwani Bharat N, Bhatia Smita, Schumacher Fredrick R, Edlund Christopher K, Hwang Amie E, Slager Susan L, Fredericksen Zachary S, Strong Louise C, Habermann Thomas M, Link Brian K, Cerhan James R, Robison Leslie L, Conti David V, Onel Kenan

Abstract excerpt

Nodular sclerosing Hodgkin lymphoma (NSHL) is a distinct, highly heritable Hodgkin lymphoma subtype. We undertook a genome-wide meta-analysis of 393 European-origin adolescent/young adult NSHL patients and 3315 controls using the Illumina Human610-Quad Beadchip and Affymetrix Genome-Wide Human SNP Array 6.0. We identified 3 single nucleotide polymorphisms (SNPs) on chromosome 6p21.32 that were significantly...

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PMID: 22086417
DOI: 10.1182/blood-2011-03-343921
PMCID: PMC3257012

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