Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma.

doi:10.1038/ncomms3549

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Article

Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma.

Nature communications - 1 Jan 2013

Frampton Matthew, da Silva Filho Miguel Inacio, Broderick Peter, Thomsen Hauke, Försti Asta, Vijayakrishnan Jayaram, Cooke Rosie, Enciso-Mora Victor, Hoffmann Per, Nöthen Markus M, Lloyd Amy, Holroyd Amy, Eisele Lewin, Jöckel Karl-Heinz, Ponader Sabine, von Strandmann Elke Pogge, Lightfoot Tracy, Roman Eve, Lake Annette, Montgomery Dorothy, Jarrett Ruth F, Swerdlow Anthony J, Engert Andreas, Hemminki Kari, Houlston Richard S

Abstract excerpt

In addition to HLA, recent genome-wide association studies (GWASs) of Hodgkin's lymphoma (HL) have identified susceptibility loci for HL at 2p16.1, 8q24.21 and 10p14. In this study, we perform a GWAS meta-analysis with published GWAS (totalling 1,465 cases and 6,417 controls of European background), and follow-up the most significant association signals in 2,024 cases and 1,853 controls. A combined analysis...

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PMID: 24149102
DOI: 10.1038/ncomms3549
PMCID: PMC5053363

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