Article
Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
Nature genetics - 1 Aug 2009
Skibola Christine F, Bracci Paige M, Halperin Eran, Conde Lucia, Craig David W, Agana Luz, Iyadurai Kelly, Becker Nikolaus, Brooks-Wilson Angela, Curry John D, Spinelli John J, Holly Elizabeth A, Riby Jacques, Zhang Luoping, Nieters Alexandra, Smith Martyn T, Brown Kevin M
Abstract excerpt
We conducted genome-wide association studies of non-Hodgkin lymphoma using Illumina HumanHap550 BeadChips to identify subtype-specific associations in follicular, diffuse large B-cell and chronic lymphocytic leukemia/small lymphocytic lymphomas. We found that rs6457327 on 6p21.33 was associated with susceptibility to follicular lymphoma (FL; N = 189 cases, 592 controls) with validation in another 456 FL cases and...
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