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Article

Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Jan 2016

Demirci F Yesim, Wang Xingbin, Kelly Jennifer A, Morris David L, Barmada M Michael, Feingold Eleanor, Kao Amy H, Sivils Kathy L, Bernatsky Sasha, Pineau Christian, Clarke Ann E, Ramsey-Goldman Rosalind, Vyse Timothy J, Gaffney Patrick M, Manzi Susan, Kamboh M Ilyas

Abstract excerpt

OBJECTIVE: Genome-wide association studies (GWAS) in individuals of European ancestry identified a number of systemic lupus erythematosus (SLE) susceptibility loci using earlier versions of high-density genotyping platforms. Followup studies on suggestive GWAS regions using larger samples and more markers identified additional SLE loci in subjects of European descent. This multistage study was undertaken to...

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PMID: 26316170
DOI: 10.1002/art.39403
PMCID: PMC4747422

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BLK
STAT4

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