Article
Non-Hodgkin lymphoma risk and variants in genes controlling lymphocyte development.
PloS one - 1 Jan 2013
Schuetz Johanna M, Daley Denise, Leach Stephen, Conde Lucia, Berry Brian R, Gallagher Richard P, Connors Joseph M, Gascoyne Randy D, Bracci Paige M, Skibola Christine F, Spinelli John J, Brooks-Wilson Angela R
Abstract excerpt
Non-Hodgkin lymphomas (NHL) are a heterogeneous group of solid tumours of lymphoid cell origin. Three important aspects of lymphocyte development include immunity and inflammation, DNA repair, and programmed cell death. We have used a previously established case-control study of NHL to ask whether genetic variation in genes involved in these three important processes influences risk of this cancer. 118 genes in...
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