Article
Association of JAK-STAT pathway related genes with lymphoma risk: results of a European case-control study (EpiLymph).
British journal of haematology - 1 May 2011
Butterbach Katja, Beckmann Lars, de Sanjosé Silvia, Benavente Yolanda, Becker Nikolaus, Foretova Lenka, Maynadie Marc, Cocco Pierluigi, Staines Anthony, Boffetta Paolo, Brennan Paul, Nieters Alexandra
Abstract excerpt
Previous studies have suggested an important role for the Janus kinase-signal transducer and activator of transcription (JAK-STAT) signalling pathway in tumour development. Therefore, we explored genetic variants in JAK-STAT pathway associated genes with lymphoma risk. In samples of the EpiLymph case-control study we genotyped 1536 single nucleotide polymorphisms (SNPs) using GoldenGate BeadArray™ Technology...
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