Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.

doi:10.1371/journal.pgen.1003220

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.

PLoS genetics - 1 Jan 2013

Vijai Joseph, Kirchhoff Tomas, Schrader Kasmintan A, Brown Jennifer, Dutra-Clarke Ana Virginia, Manschreck Christopher, Hansen Nichole, Rau-Murthy Rohini, Sarrel Kara, Przybylo Jennifer, Shah Sohela, Cheguri Srujana, Stadler Zsofia, Zhang Liying, Paltiel Ora, Ben-Yehuda Dina, Viale Agnes, Portlock Carol, Straus David, Lipkin Steven M, Lacher Mortimer, Robson Mark, Klein Robert J, Zelenetz Andrew, Offit Kenneth

Abstract excerpt

The genetics of lymphoma susceptibility reflect the marked heterogeneity of diseases that comprise this broad phenotype. However, multiple subtypes of lymphoma are observed in some families, suggesting shared pathways of genetic predisposition to these pathologically distinct entities. Using a two-stage GWAS, we tested 530,583 SNPs in 944 cases of lymphoma, including 282 familial cases, and 4,044 public shared...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Chromosomes, Human, Pair 11

Share to Gene Expression

Share to Genome-Wide Association Study

Share to Leukemia, Lymphoid

Share to Lymphoma, Follicular

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 23349640
DOI: 10.1371/journal.pgen.1003220
PMCID: PMC3547842

Genes

LPXN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.PMID 23349640Read ↗

GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.Semantic proximity Read ↗

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.Semantic proximity Read ↗

Familial predisposition and genetic risk factors for lymphoma.Semantic proximity Read ↗

Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.Semantic proximity Read ↗

Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.Semantic proximity Read ↗

A meta-analysis of genome-wide association studies of follicular lymphoma.Semantic proximity Read ↗

A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region.Semantic proximity Read ↗

Genetic associations with lymphomas in Polish patients: A pooled-DNA genome-wide association analysis.Semantic proximity Read ↗

Multi-locus HLA class I and II allele and haplotype associations with follicular lymphoma.Semantic proximity Read ↗

Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.Semantic proximity Read ↗

Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development.Semantic proximity Read ↗

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.