A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).

doi:10.1038/ng.696

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Article

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).

Nature genetics - 1 Dec 2010

Enciso-Mora Victor, Broderick Peter, Ma Yussanne, Jarrett Ruth F, Hjalgrim Henrik, Hemminki Kari, van den Berg Anke, Olver Bianca, Lloyd Amy, Dobbins Sara E, Lightfoot Tracy, van Leeuwen Flora E, Försti Asta, Diepstra Arjan, Broeks Annegien, Vijayakrishnan Jayaram, Shield Lesley, Lake Annette, Montgomery Dorothy, Roman Eve, Engert Andreas, von Strandmann Elke Pogge, Reiners Katrin S, Nolte Ilja M, Smedby Karin E, Adami Hans-Olov, Russell Nicola S, Glimelius Bengt, Hamilton-Dutoit Stephen, de Bruin Marieke, Ryder Lars P, Molin Daniel, Sorensen Karina Meden, Chang Ellen T, Taylor Malcolm, Cooke Rosie, Hofstra Robert, Westers Helga, van Wezel Tom, van Eijk Ronald, Ashworth Alan, Rostgaard Klaus, Melbye Mads, Swerdlow Anthony J, Houlston Richard S

Abstract excerpt

To identify susceptibility loci for classical Hodgkin's lymphoma (cHL), we conducted a genome-wide association study of 589 individuals with cHL (cases) and 5,199 controls with validation in four independent samples totaling 2,057 cases and 3,416 controls. We identified three new susceptibility l...

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Identifiers

PMID: 21037568
DOI: 10.1038/ng.696
PMCID: PMC4268499

Genes

GATA3
REL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21037568-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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