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Article

MDR1 gene polymorphisms and clinical relevance.

Yi chuan xue bao = Acta genetica Sinica - 1 Feb 2006

Li Yan-Hong, Wang Yong-Hua, Li Yan, Yang Ling

Abstract excerpt

In vivo and in vitro studies have demonstrated that P-glycoprotein (P-gp) plays a very significant role in the ADME processes (absorption, distribution, metabolism, excretion) and drug-drug interaction (DDI) of drugs in humans. P-gp is the product of multidrug resistance gene (MDR1/ABCB1). Pharmacogenomics and pharmacogenetics studies have revealed that genetic polymorphisms of MDR1 are associated with alteration...

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Source

Identifiers

PMID: 16529292
DOI: 10.1016/S0379-4172(06)60027-9

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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