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Article

Single nucleotide polymorphisms in ABCC2 and ABCB1 genes and their clinical impact in physiology and drug response.

Cancer letters - 8 Mar 2006

Wada Morimasa

Abstract excerpt

Among the ABC proteins, some members including ABCB1, ABCC1, ABCC2 and ABCG2 are believed to contribute to multidrug resistance of cancer chemotherapy. In addition, the broad substrate-specificity and apical localization of the ABCB1 and ABCC2 in mucosal epithelium of intestine and hepatocyte give them a protective role against xenobiotics. The inter-individual variations in activity and expression levels of...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Source

Identifiers

PMID: 16377077
DOI: 10.1016/j.canlet.2005.06.050

Genes

ABCB1
ABCC2
ABCC1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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