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Article

Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition.

The Journal of pharmacology and experimental therapeutics - 1 Aug 2002

Gerk Phillip M, Vore Mary

Abstract excerpt

The multidrug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter accepting a diverse range of substrates, including glutathione, glucuronide, and sulfate conjugates of many endo- and xenobiotics. MRP2 generally performs excretory or protective roles, and it is expressed on...

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Source

Identifiers

PMID: 12130697
DOI: 10.1124/jpet.102.035014

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12130697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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