Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis.

The American journal of pathology - 1 Jan 2012

Snelgrove Sarah L, Kausman Joshua Y, Lo Cecilia, Lo Camden, Ooi Joshua D, Coates P Toby, Hickey Michael J, Holdsworth Stephen R, Kurts Christian, Engel Daniel R, Kitching A Richard

Abstract excerpt

Unilateral ureteral obstruction (UUO) is a well-characterized murine model of renal inflammation leading to fibrosis. Renal dendritic cells (DCs) constitute a significant portion of kidney leukocytes and may participate in local inflammation and have critical roles in antigen presentation. The heterogeneity in renal DC populations and surface marker overlap with monocytes/macrophages has made studying renal DCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD11c Antigen
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrosis

Share to Lymphocyte Activation

Share to Nephritis

Share to T-Lymphocytes

Share to Ureter

Share to Ureteral Obstruction

Source

Identifiers

PMID: 22079432
DOI: 10.1016/j.ajpath.2011.09.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis.PMID 22079432Read ↗

Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis.Semantic proximity Read ↗

Dendritic cells and macrophages in the kidney: a spectrum of good and evil.Semantic proximity Read ↗

Dendritic cells in acute kidney injury: cues from the microenvironment.Semantic proximity Read ↗

Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy.Semantic proximity Read ↗

Dendritic Cells and Macrophages: Sentinels in the Kidney.Semantic proximity Read ↗

Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions.Semantic proximity Read ↗

Immune-mediated Tubule Atrophy Promotes Acute Kidney Injury to Chronic Kidney Disease TransitionSemantic proximity Read ↗

The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury.Semantic proximity Read ↗

Structure and function of renal macrophages and dendritic cells from lupus-prone mice.Semantic proximity Read ↗

Resident macrophages reprogram toward a developmental state after acute kidney injurySemantic proximity Read ↗

Altered immune cell phenotypes within chronically ischemic human kidneys distal to occlusive renal artery disease.Semantic proximity Read ↗

Conventional Type 1 Dendritic Cells (cDC1) in Human Kidney Diseases: Clinico-Pathological Correlations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.