Article
Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2013
Kawakami Takahisa, Lichtnekert Julia, Thompson Lucas J, Karna Prasanthi, Bouabe Hicham, Hohl Tobias M, Heinecke Jay W, Ziegler Steven F, Nelson Peter J, Duffield Jeremy S
Abstract excerpt
Recent reports have highlighted greater complexity, plasticity, and functional diversity of mononuclear phagocytes (MPCs), including monocytes, macrophages, and dendritic cells (DCs), in our organs than previously understood. The functions and origins of MPCs resident within healthy organs, especially in the kidney, are less well understood, whereas studies suggest they play roles in disease states distinct from...
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