Article

Immune-mediated Tubule Atrophy Promotes Acute Kidney Injury to Chronic Kidney Disease Transition

2022-06-01

Abstract excerpt

<h4>ABSTRACT</h4> Incomplete repair after acute kidney injury (AKI) is associated with progressive loss of tubular cell function and development of chronic kidney disease (CKD). Here, we compared mice subjected to either unilateral ischemia-reperfusion kidney injury with contralateral nephrectomy (IRI/CL-NX, in which tubule repair predominates) or unilateral IRI with contralateral kidney intact (U-IRI, in which f...

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Literature Corpus work: a63fd7c0-e14e-579e-aa00-5734a900d17c
DOI: 10.1101/2022.06.01.494328

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