Article
Conventional Type 1 Dendritic Cells (cDC1) in Human Kidney Diseases: Clinico-Pathological Correlations.
Frontiers in immunology - 1 Jan 2021
Chen Titi, Cao Qi, Wang Ruifeng, Zheng Guoping, Azmi Farhana, Wang Jeffery, Lee Vincent W, Wang Yuan Min, Yu Hong, Patel Manish, P'ng Chow Heok, Alexander Stephen I, Rogers Natasha M, Wang Yiping, Harris David C H
Abstract excerpt
Background: cDC1 is a subset of conventional DCs, whose most recognized function is cross-presentation to CD8+ T cells. We conducted this study to investigate the number and location of cDC1s in various human kidney diseases as well as their correlation with clinico-pathological features and CD8+ T cells. Methods: We analyzed 135 kidney biopsies samples. Kidney diseases included: acute tubular necrosis (ATN),...
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