DNA sequence analysis of gamma radiation-induced deletions and insertions at the APRT locus of hamster cells.

doi:10.1002/mc.2940030411

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Article

DNA sequence analysis of gamma radiation-induced deletions and insertions at the APRT locus of hamster cells.

Molecular carcinogenesis - 1 Jan 1990

Miles C, Sargent G, Phear G, Meuth M

Abstract excerpt

Gamma radiation-induced gene rearrangements at the Chinese hamster ovary cell locus coding for the purine salvage enzyme adenine phosphoribosyl transferase (APRT) consist of both simple deletions and more complex alterations that are presumably the result of multiple strand breaks. To characteriz...

Topics

Adenine Phosphoribosyltransferase
Animals
Base Sequence
Cells, Cultured
Chromosome Deletion
Chromosome Mapping
Cricetinae
Cricetulus
DNA
Gamma Rays
Molecular Sequence Data
Mutation
Repetitive Sequences, Nucleic Acid

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