Article
Nonhematopoietically derived DNA is shorter than hematopoietically derived DNA in plasma: a transplantation model.
Clinical chemistry - 1 Mar 2012
Zheng Yama W L, Chan K C Allen, Sun Hao, Jiang Peiyong, Su Xiaoxi, Chen Eric Z, Lun Fiona M F, Hung Emily C W, Lee Vincent, Wong John, Lai Paul B S, Li Chi-Kong, Chiu Rossa W K, Lo Y M Dennis
Abstract excerpt
BACKGROUND: Plasma DNA is predominantly hematopoietic in origin. The size difference between maternal- and fetal-derived DNA in maternal plasma prompted us to investigate whether there was any discrepancy in molecular size between hematopoietically and nonhematopoietically derived DNA in plasma. METHODS: Plasma DNA samples from 6 hematopoietic stem cell transplant recipients and 1 liver transplant recipient were...
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