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Article

Size Distributions of Maternal and Fetal DNA in Maternal Plasma

1 Jan 2004

Abstract excerpt

BACKGROUND: The discovery of fetal DNA in maternal plasma has opened up an approach for noninvasive prenatal diagnosis. Despite the rapid expansion in clinical applications, the molecular characteristics of plasma DNA in pregnant women remain unclear. METHODS: We investigated the size distribution of plasma DNA in 34 nonpregnant women and 31 pregnant women, using a panel of quantitative PCR assays with different...

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Identifiers

PMID: 14709639
DOI: 10.1373/clinchem.2003.024893

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