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Article

Predominant Hematopoietic Origin of Cell-free DNA in Plasma and Serum after Sex-mismatched Bone Marrow Transplantation

1 Mar 2002

Abstract excerpt

BACKGROUND: Despite current interest in the biology and diagnostic applications of cell-free DNA in plasma and serum, the cellular origin of this DNA is poorly understood. We used a sex-mismatched bone marrow transplantation model to study the relative contribution of hematopoietic and nonhematopoietic cells to circulating DNA. METHODS: We studied 22 sex-mismatched bone marrow transplantation patients. Paired...

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PMID: 11861434
DOI: 10.1093/clinchem/48.3.421

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